Enterovirus PCR Detection

Analyte specific reagents for Enterovirus

Bothell, WA, November 7, 2023 — ELITechGroup MDx LLC (EGMDx) announced availability of their redesigned enterovirus and parechovirus analyte specific reagents* (ASR). The ASRs are designed to be used in the development of real-time PCR assays and were reengineered for both performance and workflow functionality. The two sets of reagents are now optimized for singleplex PCR efficiency and biplex compatibility, offering greater flexibility for clinical and research laboratories.

Enterovirus Lab Tests

The company projects that many children’s hospitals will appreciate their enterovirus and Parechovirus real-time PCR design improvements. Viral meningitis is a concern among children’s hospitals, with diagnostic testing for enterovirus in cerebrospinal fluid specimens by PCR recognized as the gold standard. For this pediatric patient population, clinicians also frequently consider and order Parechovirus testing. The company notes that with regard to enterovirus respiratory testing, their probe retains its ability to detect Enterovirus D68.

PCR Testing for Enterovirus

“Our newly released enterovirus and Parechovirus reagents have been eagerly anticipated by several of our children’s hospital lab customers,” said Scott Johnston, General Manager. Johnston added, “R&D recently completed a redesign of our enterovirus and Parechovirus ASRs. The new ASRs are optimized for improved PCR efficiency at lower copy numbers and minimal cross reactivity when biplexed. Lab workflow was also top of mind during product development. We wanted to offer a workflow solution for enterovirus and Parechovirus testing, with automated extraction, amplification, and results. This automation is possible using our ELITe BeGenius® system. Alternately for lab flexibility, our reagents are compatible with many open channel systems and can help optimize the use of existing molecular lab equipment.”


Enterovirus PCR Reagents

The EGMDx product portfolio includes the following analytes of interest when testing patients suspected of viral meningitis:

  • DSQ Alert™ Enterovirus v2.0 primer and probe ASRs
  • DSQ Alert Parechovirus v2.0 primer and probe ASRs
  • HSV 1&2 ELITe MGB® IVD Assay
  • MGB Alert® VZV primer and probe ASRs
  • MGB Alert HHV-6 primer and probe ASRs

*Analyte Specific Reagent. Analytical and performance characteristics are not established.

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Real-Time PCR testing for laboratories

ELITechGroup MDx set an industry standard in real-time PCR with the introduction of minor groove binder (MGB) probe technology, featured in our MGB Alert® products. MGB probe technology has long been the gold standard for hybridization probes that allow for melt curve analysis. Adding to our legacy of innovation, we now offer DSQ Alert probe technology, an evolution in MGB probe chemistry. Our DSQ Alert reagents feature our newest proprietary duplex stabilizing quencher chemistry in hydrolysis probes, offering enhanced signal-to-noise fluorescence and DNA duplex stability. All test reagents may be used on ELITechGroup MDx proprietary instrument systems and on most open channel platforms. 

Our PCR offerings

High Throughput Reagents

Master Mixes

In Development

  • HT HDV
  • HT HSV 1&2/VZV
  • HT Legionella
  • HT Norovirus GI/II

§Analyte Specific Reagent. Analytical and performance characteristics are not established.
For Research Use Only. Not for use in diagnostic procedures.





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21720 23rd Drive SE, Suite #150

Bothell, WA 98021

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