Candida auris PCR

Real-time PCR for Candida auris

CDC considers C. auris a serious health threat for three main reasons: C. auris is difficult to identify with standard laboratory methods, is often multi-drug resistant, and causes outbreaks in healthcare settings.*
C. auris infections nearly doubled between 2019 and 2021, growing from 756 to 1,471 in two years. C. auris has now been found in more than half of U.S. states.**
Detect and identify C. auris properly with our lab test reagents.

*Centers for Disease Control and Prevention. (2021, July 22). Candida auris. Centers for Disease Control and Prevention. Retrieved March 28, 2023 from https://www.cdc.gov/fungal/candida-auris/index.html

** Lyman M et al. Worsening Spread of Candida auris in the United States, 2019 to 2021. Ann Intern Med. 2023 Mar 21. doi: 10.7326/M22-3469. Epub ahead of print. PMID: 36940442.

Candida auris PCR for fungal detection and identification

Our Candida auris real-time PCR reagents are designed to provide accurate detection of this emerging fungus. The EGMDx research and development team designed our ASR^§ and RUO^‡ reagents to meet the needs of CLIA high-complexity clinical labs and reference laboratories, allowing your own lab’s design creativity in developing an LDT (laboratory developed test) or in C. auris research.

C. AURIS TESTING PORTFOLIO

C. auris detection and amplification

C. auris echinocandin resistance mutation detection

C. auris fluconazole resistance mutation detection

Real-time PCR automated lab system

CANDIDA FAMILY OF PRIMERS, PROBES & REAGENTS

PRODUCT #	ELITECHGROUP PRODUCT NAME	REPORTABLE RESULTS
M800729	DSQ Alert™ Candida auris Primer Mix ASR	Candida auris
M800730	DSQ Alert Candida auris Probe Mix ASR	Candida auris
M400920	MGB Alert® Candida auris with echinocandin resistance RUO Detection Reagent	C. auris echinocandin resistance mutations present (with melt curve analysis)
M400861	MGB Alert Candida auris with fluconazole resistance RUO Detection Reagent	C. auris fluconazole resistance mutations present (with melt curve analysis)
M400869	MGB Alert Candida species with C. auris RUO Detection Reagent	C. albicans, C. auris, C. dubliniensis, C. glabrata (Nakaseomyces glabrata), C. krusei, C. parapsilosis complex, and C. tropicalis (color and melt discrimination)

^§Analyte Specific Reagent. Analytical and performance characteristics are not established.
^‡For Research Use Only. Not for use in diagnostic procedures.

INFECTIOUS DISEASE TEST PORTFOLIO

Real-Time PCR testing for laboratories

ELITechGroup MDx set an industry standard in real-time PCR with the introduction of minor groove binder (MGB) probe technology, featured in our MGB Alert^® products. MGB probe technology has long been the gold standard for hybridization probes that allow for melt curve analysis. Adding to our legacy of innovation, we now offer DSQ Alert^™ probe technology, an evolution in MGB probe chemistry. Our DSQ Alert reagents feature our newest proprietary duplex stabilizing quencher chemistry in hydrolysis probes, offering enhanced signal-to-noise fluorescence and DNA duplex stability. All test reagents may be used on ELITechGroup MDx proprietary instrument systems and on most open channel platforms.

Our PCR offerings

High Throughput Reagents

Master Mixes

In Development

HT HDV
HT HSV 1&2/VZV
HT Legionella
HT Norovirus GI/II

*IVD/EUA
^§Analyte Specific Reagent. Analytical and performance characteristics are not established.
^‡For Research Use Only. Not for use in diagnostic procedures.

MOLECULAR DIAGNOSTICS SYSTEM

The ELITe BeGenius^®

Extraction, amplification, results.

With automated extraction, amplification, and results interpretation, the ELITe BeGenius is a sample-to-result solution for your lab. A 3-hour turnaround time means up to 3 hours of walkaway time per run.

Bring more power and flexibility into your lab.

Open mode allows a customizable workflow. 24 PCR wells offer independent thermocycling capability. The ELITe BeGenius features:

Full automation with onboard extraction and real-time PCR
Total nucleic acid extraction of RNA and DNA
Open system capability
24 PCR wells, each with independent thermocycling capability
Multiple tests from each eluate
Post amplification melt curve option
Qualitative and quantitative capable
Up to 72 sample results in an 8-hour shift
Onboard cooled storage of samples, eluates, and reagents
6 optical channels with cross-talk customization
Automated results interpretation
LIS integration

About ELITechGroup

ELITechGroup Corporate

At a global corporate level, ELITechGroup is an integrated in-vitro diagnostics company that develops, manufactures and markets a wide range of diagnostic products and solutions, including reagents, instruments, and software. More than 650 employees make ELITechGroup a trusted partner in the IVD industry, serving hospitals and diagnostic laboratories in more than 100 countries through direct sales and third-party distribution.

To optimally serve customers in an ever-evolving IVD market, ELITechGroup is organized into four business units dedicated to specific IVD technologies and market segments: Molecular Diagnostics (MDx), Clinical Chemistry, Biomedical Systems, and Microbiology.

ELITechGroup in-vitro diagnostics company

ELITechGroup MDx - Molecular Diagnostics System Test Kits

ELITechGroup Molecular Diagnostics US

ELITechGroup MDx LLC is the company’s US Molecular Diagnostics entity, based in Bothell, WA. The US MDx group serves the needs of clinical and research laboratories alike, offering an extensive range of molecular diagnostics products.

The US product portfolio includes the fully automated sample-to-result ELITe BeGenius instrument system and a growing menu of infectious disease tests and reagents that feature the innovative MGB Alert and DSQ Alert^™ probe chemistries.

Why ELITechGroup?

Extensive IP portfolio

Inventors of MGB probes

cGMP compliant, ISO13485 certified

High throughput oligonucleotide manufacturing

25,000 sq. ft. corporate office in Bothell, WA

An Evolution of Real-Time PCR Chemistry

Our legacy of innovation is historic, and continues with DSQ chemistry, merging the original MGB probe and fluorescence quenchers first brought to you by ELITechGroup MDx in the 1990s.

MGB probe invented

1995

Eclipse Dark Quencher invented

1999

Pleiades probe invented

2004

AquaPhluor® dye invented

2005

MGB Alert® probe chemistry commercialized

2006

DSQ probe invented

2018