CRE PCR test
CRE ELITe MGB® Kit
Carbapenem-Resistant Enterobacteriaceae (CRE) are a group of bacteria that have developed resistance to carbapenems, the antibiotics of “last resort.” These resistant bacteria pose a significant threat in healthcare settings, leading to serious infections that are challenging to treat, resulting in higher morbidity and mortality rates among hospitalized patients. Rapid and reliable detection of CRE using molecular methods is crucial for identifying infected individuals, implementing effective infection control measures, and preventing outbreaks in hospitals and healthcare facilities.
The CRE ELITe MGB® Kit is a multiplex real-time PCR assay designed for the accurate detection and differentiation of the primary classes of Carbapenem-Resistant Enterobacteriaceae genes. This includes:
This assay is CE-IVD validated and can be used on various sample types, providing flexibility and reliability in clinical diagnostics. When combined with the ELITe InGenius®, a fully automated sample-to-result solution, laboratories can enhance their workflow efficiency and improve patient outcomes.
Carbapenem-Resistant Enterobacteriaceae Real-Time PCR Assay
The Carbapenem-Resistant Enterobacteriaceae Real-Time PCR Assay is a cutting-edge diagnostic tool designed for the rapid and accurate detection of CRE pathogens in clinical samples. This assay utilizes specific primers to amplify key resistance genes, including KPC, NDM, VIM, IMP, and OXA-48-like, providing high sensitivity and specificity. By employing real-time PCR technology, laboratories can monitor the amplification process in real time, allowing for quick identification of Carbapenem-Resistant Enterobacteriaceae infections. The use of this advanced assay is crucial for timely diagnosis and effective management of serious infections associated with CRE, significantly improving patient outcomes and infection control measures in healthcare settings. This CRE Real-Time PCR Assay not only enhances the detection capabilities of clinical laboratories but also contributes to better epidemiological tracking and understanding of resistance patterns among CRE strains.
CRE PCR Protocol
Detailed guidelines for performing the CRE PCR test effectively and accurately.
CRE PCR Screening
Recommended strategies for screening high-risk patient populations for CRE colonization.
CRE Genotyping PCR
Understand the genetic variations among CRE strains for better epidemiological tracking and management.
CRE PCR Primers
Key details on the design and use of CRE PCR primers for accurately amplifying Carbapenem-Resistant Enterobacteriaceae resistance genes.
Carbapenem-Resistant Enterobacteriaceae PCR
CATALOG # | PRODUCT NAME | PRODUCT DESCRIPTION |
M800692 | MGB Alert CRE RUO Detection Reagent Mix | 20X mix of primers and probes to detect and distinguish the KPC, IMP, VIM, NDM, and OXA carbapenemase genes |
§Analyte Specific Reagent. Analytical and performance characteristics are not established.
INFECTIOUS DISEASE TEST PORTFOLIO
Real-Time PCR testing for laboratories
ELITechGroup MDx set an industry standard in real-time PCR with the introduction of minor groove binder (MGB) probe technology, featured in our MGB Alert® products. MGB probe technology has long been the gold standard for hybridization probes that allow for melt curve analysis. Adding to our legacy of innovation, we now offer DSQ Alert™ probe technology, an evolution in MGB probe chemistry. Our DSQ Alert reagents feature our newest proprietary duplex stabilizing quencher chemistry in hydrolysis probes, offering enhanced signal-to-noise fluorescence and DNA duplex stability. All test reagents may be used on ELITechGroup MDx proprietary instrument systems and on most open channel platforms.
Our PCR offerings
- Adenovirus§
- Aspergillus spp.‡
- Babesia‡
- Bartonella‡
- BKV§
- Bordetella P/PP§
- Borrelia‡
- Borrelia RF‡
- Candida auris§
- C. auris with echinocandin resistance‡
- C. auris with fluconazole resistance‡
- Candida species‡
- Carbapenem-resistant Enterobacterales (CRE)‡
- Chikungunya‡
- Chlamydia pneumoniae‡
- CMV§
- Coccidioides‡
- Cryptococcus species‡
- Dengue 1-4‡
- EBV§
- Ehrlichia/Anaplasma‡
- Enterovirus§
- GUD-1 HSV 1&2 / T. pallidum‡
- GUD-2 H. ducreyi /
C. trachomatis L1-3‡ - Hepatitis E virus‡
- HHV-6§
- HHV-8§
- Histoplasma/Blastomyces‡
- hMPV§
- HSV 1&2*
- Influenza A/B/RSV‡
- JCV§
- Legionella pneumophila§
- Legionella species§
- Malaria‡
- MG with fluoroquinolone resistance‡
- MG with macrolide resistance‡
- MPXV/OPXV‡
- MRSA/SA*
- Mucorales‡
- Mumps‡
- MTB speciation‡
- Mycoplasma pneumoniae‡
Master Mixes
In Development
- HT HDV
- HT HSV 1&2/VZV
- HT Legionella
- HT Norovirus GI/II
*IVD/EUA
§Analyte Specific Reagent. Analytical and performance characteristics are not established.
‡For Research Use Only. Not for use in diagnostic procedures.
MOLECULAR DIAGNOSTICS SYSTEM
The ELITe BeGenius®
Extraction, amplification, results.
With automated extraction, amplification, and results interpretation, the ELITe BeGenius is a sample-to-result solution for your lab. A 3-hour turnaround time means up to 3 hours of walkaway time per run.
Bring more power and flexibility into your lab.
Open mode allows a customizable workflow. 24 PCR wells offer independent thermocycling capability. The ELITe BeGenius features:
- Full automation with onboard extraction and real-time PCR
- Total nucleic acid extraction of RNA and DNA
- Open system capability
- 24 PCR wells, each with independent thermocycling capability
- Multiple tests from each eluate
- Post amplification melt curve option
- Qualitative and quantitative capable
- Up to 72 sample results in an 8-hour shift
- Onboard cooled storage of samples, eluates, and reagents
- 6 optical channels with cross-talk customization
- Automated results interpretation
- LIS integration
ELITechGroup Corporate
At a global corporate level, ELITechGroup is an integrated in-vitro diagnostics company that develops, manufactures and markets a wide range of diagnostic products and solutions, including reagents, instruments, and software. More than 650 employees make ELITechGroup a trusted partner in the IVD industry, serving hospitals and diagnostic laboratories in more than 100 countries through direct sales and third-party distribution.
To optimally serve customers in an ever-evolving IVD market, ELITechGroup is organized into four business units dedicated to specific IVD technologies and market segments: Molecular Diagnostics (MDx), Clinical Chemistry, Biomedical Systems, and Microbiology.
ELITechGroup Molecular Diagnostics US
ELITechGroup MDx LLC is the company’s US Molecular Diagnostics entity, based in Bothell, WA. The US MDx group serves the needs of clinical and research laboratories alike, offering an extensive range of molecular diagnostics products.
The US product portfolio includes the fully automated sample-to-result ELITe BeGenius instrument system and a growing menu of infectious disease tests and reagents that feature the innovative MGB Alert and DSQ Alert™ probe chemistries.
Why ELITechGroup?
Extensive IP portfolio
Inventors of MGB probes
cGMP compliant, ISO13485 certified
High throughput oligonucleotide manufacturing
25,000 sq. ft. corporate office in Bothell, WA